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Jeff Ventura, the vice president of communications for the Council for Responsible Nutrition, a trade group for the supplement industry, said in a statement that there are no direct comparators for GLP-1 drugs in the dietary supplement industry

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J Am Coll Cardiol 43:155161

The ashwagandha herbal supplement is TikToks latest health craze, sparked by users boasting its potential stress relieving and physical fitness performance benefits

Previous melanocortin agonists that failed clinical trials for general obesity share common features that constrain their therapeutic windows, including low receptor potency, poor safety profiles, and suboptimal pharmacokinetics