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Notably, controlled fluid flow introduces sustained perfusion and physiologically relevant shear forces, both of which modulate cellular behaviour and allow for a more accurate assessment of nanoparticle transport, distribution and cellular uptake than static in vitro models [175, 176]
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With the backing of 20 industry bodies and organisations, it is a culmination of robust discussions and broad consensus developed at the National Kidney Summit
PLoS One 2012;7:e45499.ArticlePubMedPMC 83
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