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It can also decrease inflammation by reducing levels of other cytokines like interleukin (IL) and tumor necrosis factor-alpha (TNF-alpha)

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RPE injury and inflammatory damage are associated with RPEC ferroptosis, and numerous studies have shown that ROS can cause retinal cell damage, leading to retinal disease

933 These results suggest that PPM1K mediates the disturbance of BCAA metabolism, regulates cerebral I/R injury by activating neuronal ferroptosis, and may serve as a therapeutic intervention target

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