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Mitochondrial fission is associated with apoptosis (51), and increased fission can lead to mitochondrial fragmentation, reduced membrane potential, and decreased ATP production

Insoluble fibre (raw kale, corn, wheat bran) adds bulk but can be tougher to break down

Failure to Adequately Inform Patients and Doctors Patients and healthcare providers rely on accurate information to make informed decisions about medication use

High-Risk Contexts Although GLP-1RA therapy is generally safe and effective, the flux-constraint framework suggests that certain populations may be more sensitive to substrate imbalance during sustained hypophagia

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