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This mechanism may be related to synergistic action on -cells (15), the hypothalamus, and the pro-opiomelanocortin (POMC) gene

Evidence from clinical and preclinical studies suggests that disruption of the HPA axis and changes in GR and MR balance are involved in the ES-induced behavioral alterations and the increased risk to develop psychopathologies later in life [162, 205,206,207,208]

It is not a dietary supplement, medication, or food product, and is not intended for human consumption

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