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Care must be taken to follow blood selenium levels as selenium deficiency and excess can both adversely affect glucose and lipid metabolism and potentiate the risk of development of type 2 diabetes in several animal studies, with less clear associations in human studies (148)

Bottom line: While morning on an empty stomach is the most recommended time for l-glutathione, the best time is ultimately the one that allows you to be consistent every single day

The Central Role of Enzymes as Biological Catalysts