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Astrocytes are also responsible for neurovascular communication and maintenance of cerebral blood flow (Oksanen et al., 2019

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Figure 2 2.1 Coronary heart disease and atherosclerosis Coronary heart disease (CHD) is a condition in which the arteries cannot supply adequate oxygenated blood to the heart

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Although much promise was seen in early stages of clinical trials with the exon-skipping ASO Drisapersen for DMD, phase 3 trials failed to achieve clinical success [98,99,100]