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The mitochondria essentially burn themselves out, leading to the profound, crushing fatigue characteristic of these conditions

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482,519 Therefore, blocking TGF- signal transduction is a critical strategy in cancer treatment

Okur MN, Fang EF, Fivenson EM, Tiwari V, Croteau DL, Bohr VA (2020) Cockayne syndrome proteins CSA and CSB maintain mitochondrial homeostasis through NAD(+) signaling

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