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12 In addition, propionate is an end-product of fermentation and thus is not cross-metabolised by the microbiota unlike acetate and butyrate

Endogenous plasma glucagon-like peptide-1 following acute dietary fibre consumption

In one of the initial long-term pivotal studies of patients with type 1 and insulin-requiring T2D where full-dose pramlintide was added to existing insulin regimens in double-blind fashion without titration, it was observed that the severe hypoglycemia event rate during the first 4 weeks of therapy was higher in the pramlintide group compared with the placebo group

Frias JP, Deenadayalan S, Erichsen L et al

However, your specific situation may require a different approach depending on your age and fertility status, underlying medical conditions like PCOS or diabetes, how long youve been on GLP-1s, how much weight youve lost, your personal fertility history, and other medications youre taking