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Peptide-drug conjugates and their targets in advanced cancer therapies

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Colocalization of HCN1/2 channels and the Na + K + pumpalpha3 isoform supports this reciprocal regulation of neuronal excitability (Kang et al., 2004)

CR-fed females showed upregulation of pathways including Lysine degradation, and Valine, leucine, and isoleucine degradation. Interestingly, DL-fed females had no significantly upregulated pathways, and indeed CR-fed females had upregulation of Valine, leucine, and isoleucine biosynthesis, while DL-fed females had downregulation of this same pathway

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