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This highlights distinctions in the volume and shapes of GLP-1R TM domain (TMD) binding cavities of GLP-1, PF 06882961 and OWL-833

PD and several related neurodegenerative disorders can also been considered as proteinopathies, in which the core neurodegeneration of nigrostriatal dopaminergic neurons in PD is also associated with a more widespread cellular deposition of alpha-synuclein 8