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The concentration of serotonin can be modulated by the gut microbiome in multiple ways [230], most notably shown by altered concentration of serotonin and its metabolites in the hippocampus of germ-free animals [231]

Systematic reviews have now established that a vaginal composition dominated by Lactobacillaceae taxa such as Lactobacillus crispatus is linked to protection against conditions such as preterm birth 151 , bacterial vaginosis 152 and progression of an HPV infection into cervical cancer 153

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[1,2] It appears to be potentially more influential on cellular activities than rhIGF-1 due to an apparent significant improvement in its biological activity