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Tirzepatide is a dual GIP/GLP-1 receptor agonist that simultaneously occupies GLP-1 and GIP receptors

For example, GLP-1As frequently display immunomodulatory properties, which appears to be noteworthy, since chronic inflammatory processes in the brain are often associated with a depressive mood in patients

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Drug-target MR analysis was used to evaluate the impact of GLP-1RAs on SA, and a two-step MR analysis was further employed to explore potential mediating factors in the T2D-SA relationship