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Homocysteine is inextricably linked to the methionine cycle and degenerative diseases and is a useful biomarker to check the efficiency of one-carbon metabolism for an individual

Moreover, there is evidence that PDS5B is also important for preventing nascent DNA degradation at stalled replication forks 7,8

Biosci Rep 34(1):e00092 Poyan Mehr A et al (2018) De novo NAD+ biosynthetic impairment in acute kidney injury in humans

Interestingly, metabolic pathways, especially lipogenesis pathways, were highly upregulated in GCSCs compared with differentiated cells

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