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Horizon Therapeutics (Tepezza) integration delivering growth Key Market Developments 20222026 Semaglutide became the world's highest-revenue drug (2024): Combined Ozempic + Wegovy sales of ~USD 26 billion in 2024 made semaglutide the best-selling drug globally displacing Keytruda and Humira

It is recommended to follow up these patients closely to understand the natural history to develop better recommendations for management

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