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In animals, it has been demonstrated to reduce AGE formation and content in the kidneys at doses ranging from a human equivalent of about 795 mg to about 1.1 g daily (Karachalias 2010

These in vitro results have been further validated in murine models of malaria infection and rheumatoid arthritis, where G6PD-d or inhibition leads to less severe proinflammatory responses to stimulation marked by reduced Th1 and Th17 differentiation, decreased proatherogenic cytokines IL-1, IL-6, IL-12, and TNF, and no impact on IL-10 and TGF (classically Treg-derived) 120,121,122,123,124

This is a catch-all category for any pharmacological substance that is not addressed by other sections of the list and is not approved for human therapeutic use by any governmental regulatory health authority

Ethical approval This study was approved by the Ethics Committee of the Plastic Surgery Hospital (Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China

Recheck concentration and units before changing anything