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United States (FDA and DSHEA) Not FDA-approved for weight loss or fat-burning claims AOD9604 was previously investigated as a potential obesity treatment, but the FDA has not approved it as a prescription medication (FDA PCAC briefing)

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This is due to misconceptions about creatinine levels, which are simply a breakage product from creatine metabolism

But each of the substances would be reviewed for potential inclusions at the PCAC either during the July 2026 meeting or before February 2027