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PLoS One 11 , e0146505 (2016)

To gain a deeper understanding of the mechanism involved in the loss of cAMP generation observed in the triple AA phospho-null mutant receptor, we repeated the cAMP assays in INS-1 832/3 GLP-1R KO cells expressing WT or triple AA mutant receptors pre-treated with the PDE4-specific inhibitor rolipram (21)

Aim for a palm-sized portion of protein at every meal