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GLP-1 receptor agonists do not directly interfere with anaesthetic drugs themselves there is no known pharmacological interaction that affects how anaesthetic agents work or are metabolised, as confirmed in the Summary of Product Characteristics (SmPC) for these medications

BMJ 358 , j4008 (2017)

Surgery can decrease or eliminate pain permanently

A clinical trial of sitagliptin in a small sample of patients with impaired glucose tolerance and mild T2DM found significant reductions in carotid intimal thickness in sitagliptin compared with diet control alone [122]

Because, if youre only able to eat 50%, you should make every bite as nutritious as possible protein, fiber, and hydration is the name of the game. The nature of GLP-1s makes caloric cutback easier than it sounds