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Not only does the remethylation of homocysteine contribute to methyl group synthesis, but it also serves as a means to prevent the intracellular accumulation of S-adenosylhomocysteine and an increase in plasma total homocysteine levels [14, 20, 21, 22]

The sections were mounted onto glass slides, dehydrated in ascending series of ethanol and xylenes, and coverslipped with DPX mounting medium (Merck KGaA, Darmstadt, Germany)

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Carnitine is then involved in the regulation of the acyl-CoA/CoA balance that has important consequences in the modulation of carbohydrate metabolism, lipid biosynthesis and degradation, and gene expression (Figure 1