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Graphical Abstract Similar content being viewed by others Introduction Bariatric surgery is the most effective therapy for severe obesity

Diabetes Care 48 , 13861394 (2025)

On 21 May 2026 , Lilly published the long-awaited topline results from the TRIUMPH-1 Phase 3 trial, and the data is striking: participants on the highest dose lost an average of 28.3% of their body weight at 80 weeks , with 45.3% of patients losing 30% or more a threshold previously only achievable with bariatric surgery