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La propia recomendacin de la OMS es condicional, precisamente porque todava hay incertidumbre sobre eficacia y seguridad a muy largo plazo, mantenimiento y discontinuacin

And from our own data as well as data and literature, we can see that when you provide a multidisciplinary program with the experts you see here listed on the slide, you actually can deliver more weight reduction with a wraparound program than you do with the medications as a standalone intervention

However, she subsequently improved with supportive care alone without steroid initiation or antiIL-6 therapy and was extubated and weaned off vasopressor support

This has enabled the remarkable clinical efficacy of these medications, particularly for weight loss

However, no statistical significance was found as far as liver biopsy-based outcomes were concerned [87]