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If the interaction term was not significant, it was excluded from the model and only the main effects were reported

GLP-1RA treatment enhances IL-10 secretion by M2 macrophages (133), an effect that exhibits strong concentration dependence: Low IL-10 concentrations may facilitate tumor immune evasion, whereas high concentrations promote CD8+ T cell proliferation, activation and cytotoxicity (134)

Broad Healing Spectrum: Effective across wounds, burns, muscle, bone, ligaments, cornea, nerves, and vascular tissues (PMC8275860)

This variation can affect actual weight loss trajectories compared to the calculator's estimates based on standard titration schedules

Elucidating the role of weight loss and glycaemic control in patients with type 2 diabetes