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In the chondrocytes of the iron overload model, the levels of GPX4 and SLC7A11 within the antioxidant system were lower, whereas lipid peroxidation levels, indicated by 4-HNE, were higher, and their mitochondria exhibited characteristics similar to ferroptosis (175)

In BV-2 microglia, berberine down-regulates lipopolysaccharide- or interferon--induced iNOS and cyclooxygenase-2 (COX-2) level, and inhibits inflammatory cytokines expression (for example IL-6, IL-1, TNF-) (Lu et al., 2010)

Additionally, glutathione supports immune system function by protecting immune cells from oxidative stress and supporting their optimal function

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Together, these nutrients create a powerful shield against infections and seasonal bugs