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In spite of 40 years of research the exact function of this protein is more complex than ever, but it has been found that these intracellular dimeric proteins, play a major role in the intracellular transport of endogenous compounds, metabolizes various electrophilic xenobiotics, ligand transport and thus protects cells against toxic effects [31], [87], [85]

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Some of this change may be related to fluid balance rather than fat loss

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However, its ability to produce glutathione can be compromised by poor diet, pollution, toxins, medications, stress, trauma, infections, radiation and aging