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Clinical effectiveness of currently used antidepressant drugs, which target monoaminergic systems in the brain mainly by enhancing serotoninergic and noradrenergic neurotransmission, is very often low and insufficient since approximately only one-third of the patients achieve complete remission of depressive symptoms after therapy

Individuals with deficiency are more susceptible to oxidative stress which leads to the classical, acute hemolytic anemia (favism)

This can lead to aspiration, where food or liquid gets into the lungs during surgery

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