2025;24(2):e16716
The changes in the neurotransmitter concentration associated with cerebellar atrophy in Lurcher mice, resulting from the mutation in GluR2, are not exclusive to the cerebellum, but also affect other regions of the brain (Table 1)
Without enough B12, people may feel tired, weak, foggy, or run-down
Secondary analysis using an ELISA based approach confirms GPx3 is substantially reduced in children affected with konzo To validate the findings obtained using proteomic-based applications, we sought to determine if the reduced abundance of GPx3 protein in konzo affected children as compared to their unaffected siblings could also be detected using an orthogonal ELISA-based approach
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