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Still, for gt1a, 9 out of 11 isolates with altered ISDR replicated at least 2-fold higher than the consensus (Fig

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Therefore, not only mammalian cell lines but also model organisms such as Saccharomyces cerevisiae , Drosophila melanogaster , Caenorhabditis elegans , and Arabidopsis are used to understand human diseases (Xu and Mller 2011