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This does not necessarily mean that humans have no dietary requirements for taurine, creatine or carnosine

doi: 10.1089/jir.1990.10.403 107

Phosphatidylserine: A fat-like substance in brain cells that may support sleep and cognition

Unlike sodium-glucose cotransporter-2 (SGLT-2) inhibitorsanother class of diabetes medicationssemaglutide does not alter urinary glucose levels or create a glucose-rich environment in the urinary tract that would promote bacterial growth

This encouraged scientists to begin investigating whether targeting the central nervous system could provide an effective strategy for weight loss (Capozzi, DiMarchi, Tschpp)