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The study found that some microbiota, such as Lactobacillus , Bifidobacterium and Helicobacter pylori , can induce thyroid autoimmunity by through molecular simulation, because some bacterial proteins have structural homology with human thyroid globulin (hTg)and thyroid peroxidase (TPO), and can selectively bind human TPO and Tg antibodies, and compete with natural antigens to bind autoantibodies [69, 70]

Aquilano, et al., Front

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How Retatrutide Compares to Other Weight Loss Medications It is worth noting that retatrutide achieved its weight loss results in a shorter trial duration (48 weeks) compared to semaglutide (68 weeks) and tirzepatide (72 weeks), and the weight loss curve had not yet plateaued meaning longer treatment periods may produce even greater results