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160 After multiple oral doses of 14 mg oral semaglutide, the T max of levothyroxine was delayed by 2 h, with a 12% decrease in the C max and a 33% increase in the AUC, indicating potential clinical relevance (Table 5)

Some evidence suggests that blood levels of oxytocin are highly correlated with the hormones level in cerebrospinal fluid, which is thought to reflect oxytocin activity in the brain