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The simulation applied the Ordinary Differential Equations (ODEs) to create an exploratory model by speculating the system progression and the experimental result [4] (Figure 5)

The purified FLAG-Sirt7 (WT) protein showed strong deacetylase and debutyrylase activity toward H3K36/K37, and also weakly deacetylated or debutyrylated K18/23/27 (Fig

This process can take up to 30 minutes, depending on the number of injections administered

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Treatment with 5-FU alone or IKE alone resulted in partial inhibition, with mean fold changes in tumor volume of approximately 0.5, indicating approximately 50% suppression of tumor progression