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It is a detoxifying compound

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Despite this, the PKC inhibitor bisindolylmaleimide I (Bis) does not affect cAMP augmentation within the D1/GHSR1a dimer, while pertussis toxin, an inhibitor of the G i/o pathway, eliminates cAMP augmentation (Jiang et al., 2006)

A rescue factor abolishing neuronal cell death by a wide spectrum of familial Alzheimers disease genes and Abeta