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TARGETING MSTN IN METABOLIC DISORDERS: THERAPEUTIC POTENTIAL AND CLINICAL PROSPECTS As previously mentioned, higher serum MSTN levels have been observed in obese adults without other systemic diseases, and these individuals also exhibited reduced insulin sensitivity.[27] In addition, changes in the adiponectin levels, a key adipose-derived hormone that influences insulin sensitivity and glucose metabolism, have been reported to correlate with serum MSTN levels
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Moreover, FMT studies validated that the microbiota-modulating properties of AMP1-1 significantly alleviated weightlessness-induced bone loss
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