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Chemoinformatic database building and in silico hit-identification of potential multi-targeting bioactive compounds extracted from mushroom species

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The cellular studies using CHO cells indicated that the pre-treatment of DSePA significantly upregulated the mRNA expressions of seleno-GPxs ( GPx1 , GPx2 , GPx3 , and GPx4 ), increased total GPx activity, and concurrently improved the viability of irradiated cells with a dose modification factor of 1.53 [85]

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