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[DOI] [PMC free article] [PubMed] [Google Scholar] 120.Louie S.M., Grossman E.A., Crawford L.A., Ding L., Camarda R., Huffman T.R., Miyamoto D.K., Goga A., Weerapana E., Nomura D.K

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The process of vitrification, or glassy freezing, has been shown to reduce MMP, thereby diminishing the efficiency of oxidative phosphorylation and adversely affecting mitochondrial function and oocyte development (46)

doi: 10.1016/s1097-2765(01)00323-9 266 AnWGKanekalMSimonMCMaltepeEBlagosklonnyMVNeckersLM

Although a trend toward reduced HCC risk was observed, this failed to achieve statistical significance in the overall analysis (IRR: 0.82, 95%CI: 0.61-1.11, P = 0.189), possibly reflecting insufficient follow-up duration to capture the full impact on hepatocarcinogenesis