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Lipo B12 injections are generally very safe, but some mild and temporary side effects may include: Soreness or tenderness at the injection site Skin redness or irritation around the injection area Headache Nausea Dizziness Fatigue Diarrhea Severe allergic reactions are rare

J Clin Endocrinol Metab (2018) 103:2291301

What side effects are commonly reported

Glutathione peroxidase catalyzes the reduction of hydroperoxides, including hydrogen peroxide, by reduced glutathione and functions to protect the cell from oxidative damage

We speculated that the reduction in locomotion in ABX mice was associated with the interoception of the gut, specifically appetite