can you take zofran with tirzepatide Is anyone on Ondansetron (Zofran) daily… forever? : r/tirzepatidecompound 5 Zepbound Interactions You Should

Cold sensitivity whilst taking tirzepatide is not a recognised adverse reaction in clinical trials or the SmPC, but is anecdotally reported by some patients

Hammoud, R., & Drucker, D

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reported in approximately 4060% of participants in higher-dose groups Vomiting reported in approximately 2030% of participants at higher doses Diarrhoea Constipation Decreased appetite (which, whilst contributing to weight loss, can also be uncomfortable) The majority of gastrointestinal events were mild to moderate in severity and tended to diminish over time as participants adjusted to the medication

In fact, clinical trial data shows improvements in psychological wellbeing in people taking tirzepatide