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Contrary to other treatment options, higher concentrations in respiratory secretions can be achieved with aerosol therapy

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Adopting this technology will enable researchers to investigate how pathological shear flow and endothelial permeability contribute to the progression of the condition, offering a sophisticated environment to assess vasculature-targeted therapeutics and drug efficacy

doi:10.1074/jbc.M209372200

Data availability The mass spectrometry data generated in this study have been deposited in the ProteomeXchange Consortium via the PRIDE partner repository under PXD045265 (ECN90 -cells) [ = PXD045265] and PXD045211 (primary human islets) [ = PXD045211]