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Clinical practice suggests that antithyroid drugs combined with -adrenergic receptor antagonists can be used as effective drugs for the treatment of mental disorders and psychiatric symptoms caused by hyperthyroidism, as the excessive activation of the adrenal system induced by hyperthyroidism can lead to somatic symptoms ( Additionally, psychosomatic synchronization therapy is considered to be suitable for GD patients with psychiatric symptoms (185), as research has shown that the combination of antithyroid, antipsychotic drugs and psychotherapy contribute to the prognosis of the disease (186)

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This indiscriminate iron removal disrupts vital intracellular iron-dependent processes, such as mitochondrial respiration, DNA synthesis and repair, and redox reactions (Pea-Montes et al., 2024