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The Biology of Weight Rebound To comprehend the mechanics of regaining GLP-1 , we must first look at how these drugs function

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Next, semaglutide can cause uncomfortableand rarely, dangerousside effects or complications if given in incorrect doses or not taken correctly

In a Phase 2 randomised controlled trial published in the New England Journal of Medicine in 2023 (Jastreboff et al., NEJM 2023), adults with obesity (without type 2 diabetes) who received the highest dose of retatrutide (12 mg weekly) achieved a mean body weight reduction of approximately 24% over 48 weeks