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This medications safety profile has not been studied in patients under the age of 18, pregnant and lactating people, or those with normal BMIs. At the time of publishing, the FDA has only approved three GLP-1 agonists for weight loss: Wegovy (semaglutide), Zepbound (tirzepatide), and Saxenda (liraglutide)

Financial Times reported this week that Lilly and Novo, the manufacturers of all four GLP-1 drugs commonly used for obesity therapy, are spending $3.5 billion this year to purchase smaller companies with promising anti-obesity therapies

Missing two or more consecutive weeks resets your GLP-1 tolerance

Random tests are typically conducted under DOT regulations for safety-sensitive positions (covered separately below) or under employer-specific policies for non-DOT workplaces