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Tirzepatide has been shown to positively affect blood pressure, possibly due to improved endothelial function or decreased inflammation

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Consistent with this, the depletion of butyrate-producing bacteria and the concomitant reduction in intestinal butyrate levels reported in IBD patients compared with healthy individuals have highlighted the immunomodulatory role of this microbial metabolite (91, 100102)

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Magiakou et al