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These commenters expressed concern that calculating and reporting the measure creates significant administrative and financial burden and diverts limited resources from patient care without providing commensurate value or improving patient safety

The activation of sirtuins, proteins strongly associated with longevity, provides additional anti-aging benefits

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Comment: A commenter requested that CMS reassign CPT code 43265 to APC 5362 (Level 2 Laparoscopy and Related Services), which had a proposed payment rate of $10,966.50, due to the similarity to CPT code 47554 (Biliary endoscopy, percutaneous via t-tube or other tract