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The most common plan of action has been to hold the GLP-1 RA for at least the first cycle to monitor for unwanted effects

Primary causes of muscle-related discomfort include: Injection site reactions, affecting 0.2% to 1.2% of users [7] Dehydration from digestive side effects Rapid weight loss leading to muscle mass changes Exercise-related soreness from new fitness routines A particularly noteworthy concern is the potential for sarcopenia, characterized by the loss of muscle mass, strength, and function

Nielsen NH & Menn T (1992) Allergic contact sensitization in an unselected Danish population -- the Glostrup allergy study, Denmark