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3 While these newly issued warnings serve as a timely reminder of the importance of black-box warnings, older black-box warnings also cover large areas of psychiatric prescribing, including all medications indicated for treating psychosis or schizophrenia (increased mortality in patients with dementia), and all psychotropic medications with a depression indication (suicidality in younger people)
Monitor treatment response over time Report adverse effects promptly Clear distinction should be made between medical indications and cosmetic use to support informed decision-making
N Engl J Med, Online ahead of print, doi: 10.1056/NEJMoa2416394
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