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10,23,25 One cross-sectional study involving a cohort of patients with diverse causes of CKD showed that increased HIF pathway activity in the glomerular compartment was more common in patients with nephrosclerosis and was associated with decreased estimated glomerular filtration rate
In these cases, your GP should arrange intramuscular hydroxocobalamin injections according to NICE guidelines, with the regimen depending on whether neurological symptoms are present (as detailed in the previous section)
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