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Real-world data from over 9,900 patients showed an average of 14.1% weight loss at one year - consistent with trial findings

Patients should be counselled on red flag symptoms before initiating treatment

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Still, Wong and colleagues concluded that semaglutide could have a significant impact on reducing health care costs associated with obesity and CVD. The ongoing SELECT trial will document the actual impact of semaglutide treatment on cardiovascular outcomes in high-risk adults and established CVD and without diabetes, they wrote.

Summary: Coke Zero contains approximately 1 kcal per 330 ml can and can support a calorie deficit by replacing higher-calorie sugary drinks, though it should complement not replace a balanced, whole-food diet