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Chronic exposure to MDMA (ecstasy) increases DNA damage in sperm and alters testes histopathology in male rats

Thats why scientists are investigating how these drugs might: Reduce cravings for drugs and alcohol Curb compulsive behaviors like gambling, overeating or excessive shopping Improve mood and emotional regulation Blunt dopamine spikes associated with addictive behaviors In animal studies, GLP-1 medications have shown promise in reducing self-administration of addictive substances like cocaine, alcohol and nicotine

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doi: 10.1016/j.abb.2008.01.028 270

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