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These results suggested that FUS stimulation in the brainstem can recapitulate the hypolocomotion phenotype similar to ABX mice

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Treatment with LC in the MSG + LC 200 group significantly raised the mRNA expressions of Star and Cyp11a1 in comparison with the MSG group ( p = 0.019 and p = 0.01, respectively), while increase in the mRNA expression of Hsd17b3 was not significant

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The titration exists to let your body adapt to the GLP-1 receptor activation progressively